Transforming biological data into predictive health intelligence.
Manifold Health is an AI-native platform that models health cost trajectories from real biomarker data.
Transforming biological data into predictive health intelligence.
Manifold Health is an AI-native platform that models health cost trajectories from real biomarker data.
Smarter teams are moving to structured risk assessment.
“Built for organizations that bear health risk. Manifold Health gives teams real-time clarity, built-in structure, and smarter control based in biology.”
Jerome Scelza
Ceo & Founder
Jerome Scelza
Ceo & Founder
74% of lifestyle-related deaths are caused by chronic conditions.
74% of lifestyle-related deaths are caused by chronic conditions.
74% of lifestyle-related deaths are caused by chronic conditions.
>53% reduction in prescription use among ages 45-79.
>53% reduction in prescription use among ages 45-79.
>53% reduction in prescription use among ages 45-79.
Chronic conditions can cost up to seven times more than if they had been prevented.
Chronic conditions can cost up to seven times more than if they had been prevented.
Chronic conditions can cost up to seven times more than if they had been prevented.
Join the teams moving beyond historical claims.
Our clients include forward-thinking brokers, TPA's, and underwriters — all redefining how modern benefits teams work.
Everything your health plan needs, from risk to outcomes
Manifold removes the friction from population health and cost management — no fragmented data, no lagging claims. Monitor biological risk, forecast healthcare spend, and guide interventions in a single, AI-native platform, so your team can move faster and make better decisions.
Risk screening and stratification
Forward-looking modeling
Escalations and adjustments
Risk Monitoring
A9F3K7Q2
Risk 1
Good
80061
M4Z8R1T9
Risk 3
Flagged
Approved
83036
Q7B2XK5A
Risk 1
Good
80053
8CJF2R6M
Risk 2
Processing
85025
P9T4A7XK
Risk 2
Good
84443
1 flagged case
Resolve
Export
Risk Monitoring
A9F3K7Q2
Risk 1
Good
80061
M4Z8R1T9
Risk 3
Flagged
Approved
83036
Q7B2XK5A
Risk 1
Good
80053
8CJF2R6M
Risk 2
Processing
85025
P9T4A7XK
Risk 2
Good
84443
1 flagged case
Resolve
Export
Risk Monitoring
A9F3K7Q2
Risk 1
Good
80061
M4Z8R1T9
Risk 3
Flagged
Approved
83036
Q7B2XK5A
Risk 1
Good
80053
8CJF2R6M
Risk 2
Processing
85025
P9T4A7XK
Risk 2
Good
84443
1 flagged case
Resolve
Export
Get a real-time view of health risk across your population.
Manifold continuously models biological signal, flags emerging risk, and makes population health visibility effortless.Member Spend Oversight
A9F3K7Q2
$43,789 / $49,700
87%
M4Z8R1T9
$24,713 / $38,300
64%
Q7B2XK5A
$11,244 / $29,800
38%
8CJF2R6M
$42,700 /
$
5
4
3
2
4
,
3
2
1
0
00
9
8
6
5
4
3
%
P9T4A7XK
$13,300 / $20,900
63%
L9T4A2AM
$16,870 / $31,100
54%
Edit budget
Spend breakdown
Set alerts
Duplicate
Archive
Edit budget for Finance department?
The current monthly budget is $44,300.
Please enter
the new amount.
0.00
Cancel
Confirm
Member Spend Oversight
A9F3K7Q2
$43,789 / $49,700
87%
M4Z8R1T9
$24,713 / $38,300
64%
Q7B2XK5A
$11,244 / $29,800
38%
8CJF2R6M
$42,700 /
$
5
4
3
2
4
,
3
2
1
0
00
9
8
6
5
4
3
%
P9T4A7XK
$13,300 / $20,900
63%
L9T4A2AM
$16,870 / $31,100
54%
Edit budget
Spend breakdown
Set alerts
Duplicate
Archive
Edit budget for Finance department?
The current monthly budget is $44,300.
Please enter
the new amount.
0.00
Cancel
Confirm
Budget oversight
Marketing
$43,789 / $49,700
87%
Design
$24,713 / $38,300
64%
Sales
$11,244 / $29,800
38%
Finance
$42,700 /
$
5
4
3
2
4
,
3
2
1
0
00
9
8
6
5
4
3
%
HR
$13,300 / $20,900
63%
Ops
$16,870 / $31,100
54%
Edit budget
Spend breakdown
Set alerts
Duplicate
Archive
Edit budget for Finance department?
The current monthly budget is $44,300.
Please enter
the new amount.
0.00
Cancel
Confirm
Budget oversight
Marketing
$43,789 / $49,700
87%
Design
$24,713 / $38,300
64%
Sales
$11,244 / $29,800
38%
Finance
$42,700 /
$
5
4
3
2
4
,
3
2
1
0
00
9
8
6
5
4
3
%
HR
$13,300 / $20,900
63%
Ops
$16,870 / $31,100
54%
Edit budget
Spend breakdown
Set alerts
Duplicate
Archive
Edit budget for Finance department?
The current monthly budget is $44,300.
Please enter
the new amount.
0.00
Cancel
Confirm
Set dynamic thresholds for members, cohorts, or populations. Manifold Health continuously tracks biological risk, issues early alerts, and helps teams intervene before rising risk turns into cost.
Your reports
Spend patterns
Burn rate report - Q2
July 18, 2025
Spend categorization
Category Breakdown - June 2025
July 3, 2025
Generate report
Downloading report
Download complete!
Edit budget
Spend breakdown
Set alerts
Duplicate
Archive
Edit budget for Finance department?
The current monthly budget is $44,300.
Your reports
Spend patterns
Burn rate report - Q2
July 18, 2025
Spend categorization
Category Breakdown - June 2025
July 3, 2025
Generate report
Downloading report
Download complete!
Your reports
Spend patterns
Burn rate report - Q2
July 18, 2025
Spend categorization
Category Breakdown - June 2025
July 3, 2025
Generate report
Your reports
Spend patterns
Burn rate report - Q2
July 18, 2025
Spend categorization
Category Breakdown - June 2025
July 3, 2025
Generate report
Downloading report
Download complete!
Your reports
Spend patterns
Burn rate report - Q2
July 18, 2025
Spend categorization
Category Breakdown - June 2025
July 3, 2025
Generate report
Generate insights in seconds — from population risk to cost forecasts. Share clean, executive-ready reports or let Manifold deliver continuous updates with automated intelligence.
Built-in management tools that keep your team informed
Built-in management tools that keep your team informed
Built-in management tools that keep your team informed
Eliminate bottlenecks with configurable rules for review, escalation, and action. Manifold Health routes insights to the right teams at the right time—keeping decisions fast, consistent, and aligned.
Smart Observations
Eliminate bottlenecks with configurable rules for review, escalation, and action. Manifold Health routes insights to the right teams at the right time—keeping decisions fast, consistent, and aligned.
Smart Observations
Eliminate bottlenecks with configurable rules for review, escalation, and action. Manifold Health routes insights to the right teams at the right time—keeping decisions fast, consistent, and aligned.
Smart Observations
Track intervention partners, care programs, and services in one place. Manifold compares performance, flags overlap, and helps ensure resources are directed where they reduce risk and cost most effectively.
Program Performance Management
Track intervention partners, care programs, and services in one place. Manifold compares performance, flags overlap, and helps ensure resources are directed where they reduce risk and cost most effectively.
Program Performance Management
Track intervention partners, care programs, and services in one place. Manifold compares performance, flags overlap, and helps ensure resources are directed where they reduce risk and cost most effectively.
Program Performance Management
Finance leaders, operators, and executives each see what matters to them. Manifold Health delivers secure, role-based access so teams stay aligned without overexposing sensitive data.
Multi-User Access & Roles
Finance leaders, operators, and executives each see what matters to them. Manifold Health delivers secure, role-based access so teams stay aligned without overexposing sensitive data.
Multi-User Access & Roles
Finance leaders, operators, and executives each see what matters to them. Manifold Health delivers secure, role-based access so teams stay aligned without overexposing sensitive data.
Multi-User Access & Roles
Designed for real-world risk workflows
From setup to daily use, Manifold Health streamlines population health workflows — making risk monitoring, cost forecasting, and reporting simple from day one.
From setup to daily use, Manifold Health streamlines population health workflows — making risk monitoring, cost forecasting, and reporting simple from day one.
Easy onboarding
Manifold Health provides guided setup, data ingestion support, and clear milestones—so teams are up and running in days, not months.
Easy onboarding
Manifold Health provides guided setup, data ingestion support, and clear milestones—so teams are up and running in days, not months.
Easy onboarding
Manifold Health provides guided setup, data ingestion support, and clear milestones—so teams are up and running in days, not months.
Fast adoption
Intuitive workflows and role-based views help finance, operations, and clinical teams find value immediately—without training overhead.
Fast adoption
Intuitive workflows and role-based views help finance, operations, and clinical teams find value immediately—without training overhead.
Fast adoption
Intuitive workflows and role-based views help finance, operations, and clinical teams find value immediately—without training overhead.
Flexible integrations
Manifold Health connects to labs, claims, eligibility, and reporting systems—minimizing disruption while maximizing signal.
Flexible integrations
Manifold Health connects to labs, claims, eligibility, and reporting systems—minimizing disruption while maximizing signal.
Flexible integrations
Manifold Health connects to labs, claims, eligibility, and reporting systems—minimizing disruption while maximizing signal.
Scalable for growth
From small populations to enterprise deployments, Manifold Health adapts with role-based access, multi-entity support, and enterprise-grade controls.
Scalable for growth
From small populations to enterprise deployments, Manifold Health adapts with role-based access, multi-entity support, and enterprise-grade controls.
Scalable for growth
From small populations to enterprise deployments, Manifold Health adapts with role-based access, multi-entity support, and enterprise-grade controls.
The Manifold Health shift, straight from our users
The Manifold Health shift, straight from our users
The Manifold Health shift, straight from our users
Hear how Manifold Health is helping risk managers take control.
Hear how Manifold Health is helping risk managers take control.
Hear how Manifold Health is helping risk managers take control.
Clara Nguyen
Head of Clinical Care
“Manifold Health gave us instant visibility into spending risk across our plan. We caught three budget overruns in the first week — and now every decision is backed by real-time monitoring and data.”
37%
Reduction in budget overages
3x
Faster risk adjustments
Darius Finch
Finance Director
“Before Manifold Health, we were reacting to symptoms, fragmented data, and late-stage diagnoses. Now we have a unified view of biology, early risk signals, and predictive insight — which means fewer surprises and more time to focus on prevention and long-term health outcomes.”
3.4 h
Saved per team member each week
45%
Fewer manual reconciliation tasks
Meera Shah
Controller
“Manifold Health helped us move from reactive care to earlier insight. Our biological data is cleaner, our models are more reliable, and we finally trust the signals we’re seeing.”
48%
Faster month-end close
32%
Increase in internal team satisfaction
Clara Nguyen
Head of Clinical Care
“Manifold Health gave us instant visibility into spending risk across our plan. We caught three budget overruns in the first week — and now every decision is backed by real-time monitoring and data.”
37%
Reduction in budget overages
3x
Faster risk adjustments
Darius Finch
Finance Director
“Before Manifold Health, we were reacting to symptoms, fragmented data, and late-stage diagnoses. Now we have a unified view of biology, early risk signals, and predictive insight — which means fewer surprises and more time to focus on prevention and long-term health outcomes.”
3.4 h
Saved per team member each week
45%
Fewer manual reconciliation tasks
Meera Shah
Controller
“Manifold Health helped us move from reactive care to earlier insight. Our biological data is cleaner, our models are more reliable, and we finally trust the signals we’re seeing.”
48%
Faster month-end close
32%
Increase in internal team satisfaction
Clara Nguyen
Head of Clinical Care
“Manifold Health gave us instant visibility into spending risk across our plan. We caught three budget overruns in the first week — and now every decision is backed by real-time monitoring and data.”
37%
Reduction in budget overages
3x
Faster risk adjustments
Darius Finch
Finance Director
“Before Manifold Health, we were reacting to symptoms, fragmented data, and late-stage diagnoses. Now we have a unified view of biology, early risk signals, and predictive insight — which means fewer surprises and more time to focus on prevention and long-term health outcomes.”
3.4 h
Saved per team member each week
45%
Fewer manual reconciliation tasks
Meera Shah
Controller
“Manifold Health helped us move from reactive care to earlier insight. Our biological data is cleaner, our models are more reliable, and we finally trust the signals we’re seeing.”
48%
Faster month-end close
32%
Increase in internal team satisfaction
Start with clarity, scale with confidence
Manifold Health helps modern help plan teams move faster — with real-time visibility, flexible workflows, and automation where it matters most.
Fast onboarding
Most teams are fully live in under a week.
Built for scale
From startups to growing health plans — no bloat, no friction.
